Randy Johnson: Entering the 2008 season, he was 56 strikeouts behind Roger Clemens for second all time. Through his August 6th start against Pittsburgh, he had 114 strikeouts for the season, closing the gap to Nolan Ryan (1st all-time) to slightly under 1,000 strikeouts. http://www.enth.com/Home.aspx?q=what+pitcher+has+the+most+strikeouts
Nolan Ryan holds the record for most career strikeouts with 5.714.
Nolan Ryan with 5,714 career strikeouts.
In the modern era, the leader is Nolan Ryan, who had 383 strikeouts with the California Angels in 1973.
Steve Carlton who played his whole career with the Phillies has the most career strikeouts for a left handed pitcher, I'm not sure the exact amount though, sorry!
Randy Johnson has the most career strikeouts for a left handed pitcher with 4,875 second all time behind Nolan Ryan with 5,714.
Nolan Ryan has the most career strikeouts in the history of baseball.
Randy Johnson has the most strikeouts by a left handed pitcher. He also has the second most strikeouts all-time and over 300 wins.
currently he has 4,869 which is the most strikeouts for a left-handed pitcher, and second of all time
Johan Santana with 265 strikeouts in 2004.
Nolan Ryan has the most career strikeouts with 5,714. Randy Johnson has the 2nd most.
In 2012, Justin Verlander of the Detroit Tigers, had the most strikeouts with 239.
Sandy Koufax with 382 strikeouts in 1965.
The pitcher that had the most strikeouts in the 1960s was Bob Gibson. He had a total of 2,071, and he was also the best strikeout pitcher of the decade in the world series.