Matt Kilroy holds the record for most strikeouts by a pitcher in a single season with 513 in 1886. Nolan Ryan holds the modern day record with 383 in 1973.
Randy Johnson has the most strikeouts by a left handed pitcher. He also has the second most strikeouts all-time and over 300 wins.
In 2012, Justin Verlander of the Detroit Tigers, had the most strikeouts with 239.
As of the 2010 season, the Yankees team record for strikeouts by a pitcher in a season is 248 by Ron Guidry in 1978.
At the time of this question, Mark Buehrle had the most strikeouts, but currently Freddy Garcia does.
Camilo Pascuel
Sandy Koufax with 382 strikeouts in 1965.
The Twins record for strikeouts in a game is 15 and held jointly by Camilo Pascual, Joe Decker, Jerry Koosman, and Bert Blyleven.
bob gibson
Randy Johnson: Entering the 2008 season, he was 56 strikeouts behind Roger Clemens for second all time. Through his August 6th start against Pittsburgh, he had 114 strikeouts for the season, closing the gap to Nolan Ryan (1st all-time) to slightly under 1,000 strikeouts. http://www.enth.com/Home.aspx?q=what+pitcher+has+the+most+strikeouts
For the 2007 season, Jake Peavy of the San Diego Padres led all MLB pitchers in strikeouts with 240.
Matt Kilroy holds the record for most strikeouts by a pitcher in a single season with 513 in 1886. Nolan Ryan holds the modern day record with 383 in 1973.
Randy Johnson has the most strikeouts by a left handed pitcher. He also has the second most strikeouts all-time and over 300 wins.
In 2012, Justin Verlander of the Detroit Tigers, had the most strikeouts with 239.
15.
Nolan Ryan
As of the 2010 season, the Yankees team record for strikeouts by a pitcher in a season is 248 by Ron Guidry in 1978.