Johan Santana with 265 strikeouts in 2004.
Nolan Ryan has the most career strikeouts in the history of baseball.
Randy Johnson has the most strikeouts by a left handed pitcher. He also has the second most strikeouts all-time and over 300 wins.
Nolan Ryan has the most career strikeouts with 5,714. Randy Johnson has the 2nd most.
The pitcher that had the most strikeouts in the 1960s was Bob Gibson. He had a total of 2,071, and he was also the best strikeout pitcher of the decade in the world series.
Randy Johnson
Johan Santana with 265 strikeouts in 2004.
Nolan Ryan has the most career strikeouts in the history of baseball.
Randy Johnson has the most strikeouts by a left handed pitcher. He also has the second most strikeouts all-time and over 300 wins.
Nolan Ryan has the most career strikeouts with 5,714. Randy Johnson has the 2nd most.
15.
Nolan Ryan
The pitcher that had the most strikeouts in the 1960s was Bob Gibson. He had a total of 2,071, and he was also the best strikeout pitcher of the decade in the world series.
In 2012, Justin Verlander of the Detroit Tigers, had the most strikeouts with 239.
Sandy Koufax with 382 strikeouts in 1965.
Nolan Ryan holds the record for most career strikeouts with 5.714.
At the time of this question, Mark Buehrle had the most strikeouts, but currently Freddy Garcia does.