372 for the Arizona Diamondbacks in 2001.
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Randy Johnson
Randy Johnson - 19
Randy Johnson has the most strikeouts by a left handed pitcher. He also has the second most strikeouts all-time and over 300 wins.
actually Charles radbourn had 441 strikeouts but they still don't count that season there for nolan Ryan holds the record with 383 strikeouts
No. The most strikeouts in a nine inning game is 20 by Randy Johnson, Roger Clemens, and Kerry Wood. That left 7 outs to be made by something other than a strikeout.