As of March 1, 2008, Roger Clemens is 2nd on the all-time list for career stikeouts with 4,672. Randy Johnson is close behind with 4,616 strikeouts.
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Randy Johnson has the most strikeouts by a left handed pitcher. He also has the second most strikeouts all-time and over 300 wins.
Buddy Scholtz had 26 strikeouts in a game for Miami University.
For the stat "Strikeouts per 9 Innings" for pitchers that have pitched at least 1000 innings the all time leader, through games played on September 22, 2009 is Randy Johnson with 10.61 strikeouts per 9 innings pitched (4872 strikeouts in 4132 1/3 innings pitched).Second all time is Kerry Wood with 10.39 strikeouts per 9 innings pitched (1466 strikeouts in 1270 1/3 innings pitched) and third is Pedro Martinez with 10.05 strikeouts per 9 innings pitched (3152 strikeouts in 2823 1/3 innings pitched).
actually Charles radbourn had 441 strikeouts but they still don't count that season there for nolan Ryan holds the record with 383 strikeouts
In 2012, Justin Verlander of the Detroit Tigers, had the most strikeouts with 239.