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Through games played on September 13, 2011 that is Adam Dunn with 195 strikeouts in 2004. Drew Stubbs of the 2011 Reds has 190 strikeouts so far and will probably set a new Reds record and surpass 200.
Nolan Ryan with 5714. he had 300 strikeouts 6 times and almost 400 strikeouts. Nolan Ryan played a 28 year career.He led the American league in strikeouts 10 times.He has a record pitching a no hitter at 43 and 44 with 7 no hitters that's a record.
Sammy Sosa of the Cubs with 516 ... 174 in 1997 and 171 in both 1998 and 1999.
In 2012, Justin Verlander of the Detroit Tigers, had the most strikeouts with 239.
Johan Santana with 265 strikeouts in 2004.