Reggie Jackson struck out 2,597 times in his career. This is a Major League record.
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In MLB, that was Babe Ruth who struckout for the 1000th time in the 1930 season. Ruth was the MLB leader in career strikeouts (with 1330) until 1964 when he was surpassed by Mickey Mantle.
The pitcher that struck out the most batters in history is Nolan Ryan. He has struck out 5,714 batters during his career from September 11, 1966 until September 22, 1993.
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