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In his 21 year Major League Baseball (MLB) career, Reggie Jackson holds MLB record for most career strikeouts by a player/batter, with a career total of 2,597 strikeouts - 46 times while with the Kansas City Royals, 1,180 with the Oakland Athletics, 108 with the Baltimore Orioles, 573 times with the New York Yankees, and 690 times with the California Angels.
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