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The pitcher that struck out the most batters in history is Nolan Ryan. He has struck out 5,714 batters during his career from September 11, 1966 until September 22, 1993.

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10y ago

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More answers

Reggie Jackson struck out 2,597 times, the most in MLB history.

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11y ago
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Reggie jackson

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Anonymous

4y ago
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Q: What pitcher struck out the most batters looking in history?
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