Roger Clemens
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For the stat "Strikeouts per 9 Innings" for pitchers that have pitched at least 1000 innings the all time leader, through games played on September 22, 2009 is Randy Johnson with 10.61 strikeouts per 9 innings pitched (4872 strikeouts in 4132 1/3 innings pitched).Second all time is Kerry Wood with 10.39 strikeouts per 9 innings pitched (1466 strikeouts in 1270 1/3 innings pitched) and third is Pedro Martinez with 10.05 strikeouts per 9 innings pitched (3152 strikeouts in 2823 1/3 innings pitched).
One. The Seattle Mariners pitcher won the 2010 American League Cy Young Award despite a mediocre won-loss record (13-12). But he led the league with a 2.27 ERA, while compiling 232 strikeouts in 249.2 innings pitched.
3. Nolan Ryan's first game in MLB was September 11, 1966 against the Atlanta Braves. He pitched 2 innings and had 3 strikeouts. His first ever MLB strikeout was of Braves' pitcher Pat Jarvis.
Johan Santana with 265 strikeouts in 2004.
Randy Johnson has the most strikeouts by a left handed pitcher. He also has the second most strikeouts all-time and over 300 wins.