When do you pitch from the windup?
Generally, only when there are no runners on base. However, you
could also pitch from the windup when there is a runner only on
third base, or on 2nd and 3rd, or when the bases are loaded.
Pitching from the windup can be a problem with a runner on third
because this will allow the runner to get a longer lead off the
base than the lead the runner will get when the pitcher pitches
from the stretch.