He has never trown 50 touchdowns. Tom Brady has thrown 50, but Peyton Manning has only thrown 49 in one season.
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In his professional career, Peyton Manning has thrown for at least 26 touchdowns a year: 1999 and 2001 In his college career, he threw for; 1994 11 TDS 1995 22 TDS 1996 20 TDS 1997 37 TDS
In the NFL through the 2009 regular season, that is 472 yards (Manning threw for 5 TDs) against the Kansas City Chiefs on October 31, 2004. The Chiefs won that game 45-35.
Through the 2008 regular season, once. That was September 10, 2006 when the Peyton and the Colts defeated Eli and the Giants, 26-21. Peyton completed 25 passes in 41 attempts for 276 yards, 1 TD, and 1 INT and Eli completed 20 passes in 34 attempts for 247 yards, 2 TDs, and 1 INT.
Actually, there was no season where Jerry Rice scored 22 TDs. However, in the 1987 season, Rice scored 22 TDs from pass receptions and also scored 1 rushing TD for a total of 23.
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