In the NFL through the 2009 regular season, that is 472 yards (Manning threw for 5 TDs) against the Kansas City Chiefs on October 31, 2004. The Chiefs won that game 45-35.
In 2004, Peyton Manning threw for 4,557 yards, his most. It is likely he will break that in 2010, possibly reaching 5,000 yards (only the third QB to do it)
81.8 Manning completed 25 passes in 38 attempts for 247 yards, 1 TD, and 1 INT.
That was Jack Kemp with 21,130 passing yards with the Chargers and Bills.
288 Passing yards QB - Drew Brees
69 Yards: NFL QB Challenge. (Donovan McNabb threw 76). 69 Yards: NFL QB Challenge. (Cade Mcnown threw 72).
Through the 2008 regular season, once. That was September 10, 2006 when the Peyton and the Colts defeated Eli and the Giants, 26-21. Peyton completed 25 passes in 41 attempts for 276 yards, 1 TD, and 1 INT and Eli completed 20 passes in 34 attempts for 247 yards, 2 TDs, and 1 INT.
63 yards
Manning
Peyton Manning
81.8 Manning completed 25 passes in 38 attempts for 247 yards, 1 TD, and 1 INT.
Tom Brady, Peyton Manning, and Drew Brees
Peyton Manning was 31-45 for 333 yards compared to Drew Brees' 32-39 for 288 yards.
Among active players it is Peyton Manning but among inactive it is Dan Marino
Peyton has more in his career with 64,964 yards compared to Brady's 49,149. While Manning has been in the league two years longer than Brady, Peyton would almost certainly still have more yards
Drew Brees and Peyton Manning
Drew Brees[ Saints QB]
Colts QB Peyton Manning had 31 of 45 passes completed for 333 yards, 1 TD, and 1 interception.
For team passing yards, yes ... for individual passing yards, no. A team's total passing yards is the total of individual passing yards minus yards lost from sacks. Sacks are not considered when calculating individual passing yards.