Considering that only about 500K people have ever run the Boston Marathon in over 115 years, the answer is not very many.
If we're looking at just the US population, then that would be less than 0.2% of all Americans will run in the Boston Marathon.
If we're looking at worldwide population, then it would be less than 0.0001% of the world will run in the Boston Marathon.
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It all depends, but on average, for big-city marathons, for every 1,000 people who register for a marathon, 820 of them will start the race and about 650 will finish.
According to statistics, slightly over 50 percent of the people finish marathons. The others usually give up and drop out in the course of the marathon.