Marathon runners train their bodies so that they are prepared for the 26.2 miles of running. Each mile run during training helps condition them for the challenge.
However, when the pain hits, the battle becomes more mental than physical. The unique thing about marathon pain is that there is a completely effective way of stopping the pain - you just have to stop running. Not a very good option for someone trying to finish a marathon. So in the end, the marathon isn't so much about suppressing pain as it is running through it.
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They run in a race called a marathon. A full marathon is 26 miles 385 yards (42.195 km).