Carmelo Castillo debuted on July 17, 1982, playing for the Cleveland Indians at Cleveland Stadium; he played his final game on May 9, 1991, playing for the Minnesota Twins at Hubert H Humphrey Metrodome.
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Francisco Melendez debuted on August 26, 1984, playing for the Philadelphia Phillies at Veterans Stadium; he played his final game on October 1, 1989, playing for the Baltimore Orioles at Memorial Stadium.
Luis Castillo debuted on August 8, 1996, playing for the Florida Marlins at Joe Robbie Stadium; he played his final game on October 3, 2010, playing for the New York Mets at Citi Field.
Luis Aponte debuted on September 4, 1980 and played his final game on July 6, 1984.
Wilkin Castillo debuted on September 2, 2008, playing for the Cincinnati Reds at Great American Ball Park; he played his final game on June 20, 2009, playing for the at .
Frank Castillo debuted on June 27, 1991, playing for the Chicago Cubs at Wrigley Field; he played his final game on May 26, 2005, playing for the Florida Marlins at Dolphin Stadium.
Manny Castillo debuted on September 1, 1980, playing for the Kansas City Royals at Royals Stadium; he played his final game on October 2, 1983, playing for the Seattle Mariners at Kingdome.
Bobby Cargo debuted on October 6, 1892 and played his final game on October 7, 1892.