Luis Aponte debuted on September 4, 1980 and played his final game on July 6, 1984.
Luis Gonzalez debuted on September 4, 1990, playing for the Houston Astros at Astrodome; he played his final game on September 28, 2008, playing for the Florida Marlins at Dolphin Stadium.
Luis Atilano debuted on April 23, 2010, playing for the Washington Nationals at Nationals Park; he played his final game on July 20, 2010, playing for the Washington Nationals at Nationals Park.
Luis Avilan debuted on July 14, 2012, playing for the Atlanta Braves at Turner Field; he played his final game on September 29, 2013, playing for the Atlanta Braves at Turner Field.
Luis Garcia debuted on April 5, 1999, playing for the Detroit Tigers at Tiger Stadium; he played his final game on May 3, 1999, playing for the Detroit Tigers at Tiger Stadium.
Luis Tiant debuted on July 19, 1964, playing for the Cleveland Indians at Cleveland Stadium; he played his final game on September 4, 1982, playing for the California Angels at Anaheim Stadium.
Luis Aponte debuted on September 4, 1980, playing for the Boston Red Sox at Fenway Park II; he played his final game on July 6, 1984, playing for the Cleveland Indians at Cleveland Stadium.
Luis Aponte played in 34 games at pitcher for the Boston Red Sox in 1983, starting in none of them. He played for a total of 186 outs, equivalent to 6.89 9-inning games. He made 10 putouts, had 8 assists, and committed no errors, equivalent to 0 errors per 9-inning game. He had one double play.
Luis Aguayo debuted on April 19, 1980 and played his final game on September 30, 1989.
Luis Alcaraz debuted on September 13, 1967 and played his final game on June 7, 1970.
Luis Alicea debuted on April 23, 1988 and played his final game on September 25, 2002.
Luis Aloma debuted on April 19, 1950 and played his final game on August 30, 1953.
Luis Alvarado debuted on September 13, 1968 and played his final game on April 30, 1977.
Luis Andujar debuted on September 8, 1995 and played his final game on June 28, 1998.
Luis Aparicio debuted on April 17, 1956 and played his final game on September 28, 1973.
Luis Aquino debuted on August 8, 1986 and played his final game on September 12, 1995.
Luis Arroyo debuted on April 20, 1955 and played his final game on May 28, 1963.
Luis Atilano debuted on April 23, 2010 and played his final game on July 20, 2010.