I believe ... it was Walter Johnson. We know that he lost 26, count 'em, 26 games by the score of 1-0. However, I can't seem to find out how many other 1-run games he may have lost. Even if you take just his 1-0 losses, I think he's the one. In the post WWII era, the name Jim Tobin comes up, but I'm still researching that one.
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Yes.The most wins a pitcher in MLB has had in a season without a loss is 12. That was by Tom Zachary of the 1929 New York Yankees who pitched in 26 games and threw 119 2/3 innings.
Denny McLain, who won 16 straight road games in 1968.
Old Hoss Radbourn way back in 1884 won an amazing 59 games according to Baseball Almanac.
Most teams will use a five man rotation and based on this a starting pitcher will pitch every sixth day.
Justin Verlander