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The 2001 Seattle Mariners and 1906 Chicago Cubs have that record with 116 wins in an MLB season.This was actually done twice. First by the Chicago Cubs in 1906 with 116 wins, and then the Seattle Mariners did the same in 2001. Unlike the Mariners the Cubs had a 152 game season, so they could have achieved more wins because the Mariners season was 162 games long.
The 1906 Chicago Cubs and the 2001 Seattle Mariners hold the MLB record for wins in the regular season with 116.
Through the 2017 regular season, the two teams have played 711 games. The Houston Astros have 378 wins and 333 losses against the Chicago Cubs.
Only 13 wins.
The Cubs (1906) and Mariners (2001) who won 116 games in one season.