NFL teams play four interconference games per year. One division from the AFC plays one division from the NFC, cycling through all the divisions on a four-year rotation.
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81
1-3 games a week
162
It's depends on WHERE you play. England Premier League, Spain La Liga, and Italy Serie A play 38 games.
There are 162 games in a MLB regular season. Add that to as many as 36 exhibition games and a possible 19 post season games and MLB team could play as many as 217 games in a year.