No regular season Major League Baseball game has ever been played in Spain.
cleveland
The first Major League All-Star Game was played at Comiskey Park in Chicago, Illinois. The date was July 6, 1933 and the American League was the winner.
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Although the definition of "major league" has been argued, present day MLB, as well as the Hall of Fame, define the first "major" league as the National League founded in 1876. The link below describes the first game played in that league, on April 22, and mentions that Jim O'Rourke got the first hit in that game.
The Twins and the Yankees
first Native American to compete in Major League Baseball was Louis Sockalexis who played from 1897-1899 with a Cleveland franchise then using the title the"Spiders".
The American League grew out of the minor league Western League (founded 1893) which renamed itself the American League in October 1899. The league declared itself a major league on January 28, 1901, and played its first major league season that year.
Dwight Gooden was drafted in the first round in 1982 for the minor league. He went onto the major league in 1984and played for the New York Mets.
The first major league, the National Association, started in 1871. The National League's first year was 1876 and the American League's first year was 1901.
Jackie Robinson's first major league team was the Brooklyn Dodgers.
Jackie Robinson was able to play Major League Baseball because the Brooklyn Dodgers called him up from the minors in 1947. His first season in the majors, Robinson played first base.