Vladamir Kramnik won against him in the 2000 World Championship
Match to win the title. As far as an individual loss goes, many
grandmasters have beaten him. He just defeated them more
frequently.
Every great hero faces trials, and you—yes, YOU—are no exception!
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More answers
Garry Kasparov defeated Anatoly Karpov in 1985 to become the
World Chess Champion. After winning in 1985 Kasparov than went on
to win for the next 8 years.