Brett Favre has been injured, but he has never missed a NFL game in his career.
No!
Injured reserve list
An NFL team has 53 men on its roster not counting injured reserve.
all
how many players get injured in a year in professional football
A player on injured reserve remains on the team but cannot participate on the active roster for the remainder of the season.
they workout with the player, medically help the players if injured
New york giants
for about 4 years
In 2010, around 300 players wound up injured badly enough they went on injured reserve.
how does IR for an NFL player affect his salary