Chicago Cardinals (now the Arizona Cardinals) quarterback Jim Hardy holds the dubious distinction of throwing a NFL Record 8 interceptions in a single game against the Philadelphia Eagles, September 24, 1950.
Donald Hollas
Bret favre
Tony Romo when its all said and done!
The quarterback that has the most interceptions is Brett Favre, he has 22 interceptions
Unknown, as the 2010 NFL season has not begun yet.
Jim hardy of the cardinals threw 8 interceptions in a game in the 1950's
Deangelo Hall (4).
3
4
The player was Mitchell Price in the game Tulane vs Tennessee-Chattanooga on Sept 3, 1988 and he had 5.
The most interceptions Troy Aikman has thrown in one game is 5 vs New York Giants in the 2000 season.
Rich Gannon.