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Offensive line-men have to explode and push forward in run blocking (which is the most fun). and have to deflect and sustain defenders while pass blocking. The muscles that are used the most, would probally be: the chest (pushing motion) and thighs, hamstrings, and calfs (for accelerating and pushing their wieghts, along with the defenders forward).

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Q: What muscles does playing offensive line work?
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