Here's the all-time list as of the start of the 2008 season:
Boston REDSOX
CAREER
HOMERUNS HR
1 Ted Williams 521
2 Carl Yastrzemski 452
3 Jim Rice 382
4 Dwight Evans 379
5 Manny Ramirez 254
6 Mo Vaughn 230
7 Bobby Doerr 223
8 Jimmie Foxx 222
9 Rico Petrocelli 210
10 David Ortiz 208
11 Nomar Garciaparra 178
12 Jackie Jensen 170
T13 Carlton Fisk 162
T13 Tony Conigliaro 162
15 George Scott 154
16 Reggie Smith 149
17 Jason Varitek 148
18 Trot Nixon 133
19 Frank Malzone 131
20 Mike Greenwell 130
21 Fred Lynn 124
22 Vern Stephens 122
23 John Valentin 121
24 Joe Cronin 119
25 Troy O'Leary 117
26 Tony Armas 113
27 Dick Gernert 101
T28 Ellis Burks 94
T28 Butch Hobson 94
30 Jim Tabor 90
31 Dom DiMaggio 87
32 Brian Daubach 86
33 Wade Boggs 85
34 Rich Gedman 83
35 Dick Stuart 75
36 Mike Stanley 73
37 Gary Geiger 71
38 Jimmy Piersall 66
39 Sammy White 63
40 Eddie Bressoud 57
T41 Tom Brunansky 56
T41 Johnny Damon 56
43 Felix Mantilla 54
44 Ted Lepcio 53
T45 Phil Todt 52
T45 Kevin Millar 52
T45 Jose Canseco 52
48 Walt Dropo 51
49 Reggie Jefferson 50
T50 Bob Tillman 49
T50 Lu Clinton 49
T50 Babe Ruth 49
T50 Tim Naehring 49
T54 Doug Mirabelli 48
T54 Bill Buckner 48
T54 Carl Everett 48
T54 Buck Freeman 48
T58 Don Baylor 47
T58 Mike Andrews 47
60 Bernie Carbo 45
61 Mike Easler 43
T62 Dave Stapleton 41
T62 Mike Lowell 41
T62 Joe Foy 41
T62 Bill Mueller 41
T62 Ken Harrelson 41
T67 Tony Perez 40
T67 Clyde Vollmer 40
T67 Cecil Cooper 40
T70 Don Buddin 39
T70 Tris Speaker 39
T72 Bill Werber 38
T72 Rick Burleson 38
T74 Kevin Youkilis 37
T74 Vic Wertz 37
76 Tommy Harper 36
T77 Earl Webb 35
T77 Lee Thomas 35
T79 Hobe Ferris 34
T79 Scott Hatteberg 34
T81 Shea Hillenbrand 33
T81 Billy Conigliaro 33
T81 Jack Clark 33
84 Norm Zauchin 32
85 Roy Johnson 31
T86 Nick Esasky 30
T86 Jose Offerman 30
T86 Harry Hooper 30
T89 Bob Johnson 29
T89 Andre Dawson 29
T89 Pete Runnels 29
T89 Jim Pagliaroni 29
T93 Scott Cooper 27
T93 Ira Flagstead 27
T93 Smead Jolley 27
T93 Duffy Lewis 27
T97 Dalton Jones 26
T97 Joe Lahoud 26
T99 Jimmy Collins 25
T99 Billy Klaus 25
T99 Hoot Evers 25
Dave Klingman holds the record for most home runs hit during a retirement season. He hit 35 home runs in his 1987 final season.
Mark McGwire had over 70 home runs in one season
Barry Bonds holds the record for career home runs with 762 and the mark for most homers in a season with 73.
Dave Klingman holds the record for most home runs hit during a retirement season. He hit 35 home runs in his 1987 final season.
He holds the major league records for most home runs in a career (762) and most home runs in a season (73).
He holds the world record for the most home runs in a single season.
Coors field
As of June 2014 Barry Bonds holds the record for most regular season homeruns. The record is 73 which beat Mark McGwire's record.
David Ortiz set the single-season record for most home runs by a Boston Red Sox player in 2006. He hit 54 home runs that year, which was the most in the American League.
Nobody has hit 400 home runs in a single season in Major League Baseball history. The record for most home runs in a season is 74, set by Barry Bonds in 2001.
The record is still held by Barry Bonds.
In MLB through the 2008 season, the record for home runs by a team in one season is 264 by the 1997 Seattle Mariners.