Dave Klingman holds the record for most home runs hit during a retirement season. He hit 35 home runs in his 1987 final season.
Mexicans
In both 1965 and 1969, Rose hit 16 home runs -- the most for one year of his MLB career.
David Ortiz set the single-season record for most home runs by a Boston Red Sox player in 2006. He hit 54 home runs that year, which was the most in the American League.
250
David Ortiz began playing Major League baseball in 1997. From 1997 through the 2010 season, Ortiz hit 349 home runs.
Barry Bonds of the San Francisco Giants hit 73 home runs during the 2001 season.
Cubs and white soxs
The most home runs in a twenty five year period was from 1900-1925 , this was due to the talent that was being utilized after baseball had become popular.
Ralph Kiner and Johnny Mize both hit 51 home runs that year. Amazing to consider that the previous year's HR champ in the NL was also Kiner -- with 23 home runs!
11 home runs ***During a "series" not a game. I know the Giants had 14 one year....
The New York Mets hit 160 home runs as a team in the year 2000.