Two wild card teams from each league makes the MLB playoff each year. As of 2012 there is a one game wild card playoff between the two best records in each league who didn't win their division.
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Originally it was 8 total, 3 division winners from each league as well as 1 Wild Card winner for each league. The Wild Card winner is the team from each league that has the best record that did not win a division. However starting with the 2012 Playoffs, an additional Wild Card winner from both leagues will be added into the Playoffs so now a total of 10 teams can make the Playoffs.