There are 7 substitutes allowed. 15 men start on and 7 are there to be substituted. Once a player has been substitued off the field, he cannot come back on. If he is injured, he stays off and the same if hes not! The only times he can come back on is if he went off for blood and got stiched up again, or if he is in the front row, as these are specialist positions and someone inexperienced could get injured.
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You can make 12 changes from the 4 players on the bench. This includes bloodbins, so if a player is actively bleeding they have to use one of the interchanges to get medical attention. If all 12 interchanges have been used and a player starts bleeding they have to leave the field for treatment and the team continue playing a man short. Harsh, but it's the rules.