1) You make fair contact with the ball, and either ground-out or fly-out. 2) You take your lead to early (before the ball is released from the pitchers hand) and the base umpire catches you. 3) You strike out. 4) You foul tip the ball into the catchers glove 5) You run on a hit ball and the play is made at the bag you are attempting to advance to on a fielders choice. 6) You are running the base path and the hit ball hit you before it is fielded by the defense.
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If someone gets to the base with the ball before you, or you get tagged by the ball.