No. . . they haven't
The 2008 Detroit Lions lost all 16 regular-season games.
Chicago Cardinals (Arizona Cardinals)1943 0-10
The Lions
no one lost a game in 2008
The Detroit Lions, Losing ALL of their regular season game ending the season with 16 losses
Tampa Bay Buccaneers
The Rams only victory in the 2009 season came in Game 8 over the Detroit Lions, 17-10.
no cowboys
The Detroit Lions. They were 0-16
As of the start of the 2008 season, the Arizona Cardinals are the only franchise in the NFL to have lost 600+ games.
The New York Giants did that during the 2007 season. They lost their first game to the Dallas Cowboys 45-35 AND lost their second game to the Green Bay Packers 35-13. They went on to defeat the New England Patriots 17-14 in the Super Bowl.