Floyd Mayweather Sr. lost 6 fights in his career. He suffered defeat at the hands of Tyrone Phelps, Sugar Ray Leonard, Marlon Starling and his last three professional fights. These losses were to Clayton Hires, Marlon Starling again, and Roger Turner. His son, Floyd Mayweather Jr. is still undefeated as a pro.
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juan manuel marquez, in September '09.
boxrec.com will have the full records of both.
Floyd Mayweather won the boxing match on 9/13/2014. He wom with a unanimous decision by the judges.