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It's a build up of lactic acid. The muscles cannot process the waste products (from rapid exercising) quickly enough, and this builds up in the tissues as lactic acid. Eventually the levels get so high that the muscles seize-up.

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8y ago

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The burn is caused by the build-up of lactic acid in the muscles.

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8y ago
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Q: Why do your legs burn when you run a 3 mile race?
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