Browns running back Ernie Davis died of Leukemia in 1962, before ever getting the chance to play in the NFL. However, Ernie Davis wasn't drafted by the Browns, he was originally drafted by the Washington Redskins with the first pick in the first round of the 1962 NFL Draft.
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Jim Brown (#32) of the Cleveland Browns
He played for nine years as a running back for the Browns.
Running back Jeff Kenney was drafted in the first round, with the 23rd overall pick, by the Kansas City Chiefs in 1972.
Running back, Emmitt Smith, ran the 40 yard dash in 4.7 seconds. Smith was drafted by the Dallas Cowboys in the first round of the 1990 NFL Draft.
The pass was intended for John "Frenchy" Fuqua, who played for the Pittsburgh Steelers as a running back from 1970-1976. He was drafted by the NY Giants in 1969 in the 11th round and attended college at Morgan State.