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Most rushing touchdowns, game: 6, Ernie Nevers, November 28, 1929
Tim Renowned with 23 vs San Diego
Tiki Barber with 234 rushing yards against the Washington Redskins on December 30, 2006.
Walter Payton broke O.J. Simpson's single-game rushing record. Payton gained 275 rushing yards in a 1977 game against the Minnesota Vikings.
Marcus depree