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Peyton Manning
Brett Favre holds the record for most career touchdown passes with 508. He officially filed his retirement papers with the NFL on January 17, 2011.As of January 03, 2010, Brett Favre has thrown 497 career touchdown passes. He threw for 33 touchdowns in 2009 with only 7 interceptions.He threw for an avg of 7.9 yards per pass, the most in his career. His QB rating of 107.2 was the highest in his career.-------------As of September 30, 2007, Brett Favre has the most NFL touchdown passes with a total of 421.Brett Favre with 508 touchdown passes
The NFL Record for most touchdown passes in a game is 7. This has been done by: Sid Luckman - 1943 Adrian Burk - 1954 George Blanda - 1961 Y.A. Tittle - 1962 Joe Kapp - 1969 Peyton Manning - 2013
Jerry Rice