The record for most interceptions by a player in an NFL game is 4 and is held by about 20 different players. The last player to do it was DeAngelo Hall of the Redskins in a game against the Bears in 2010. The first player to do it was Sammy Baugh of the Redskins against the Lions in 1943. One player has done it twice ... Jerry Norton of the Cardinals intercepted 4 passes against the Redskins in 1960 and the Steelers in 1961.
The record for most career interceptions in NFL history is held by Paul Krause, who actually played safety during his 16-year careeer. He made 81 interceptions while playing for the Washington Redskins (1964-1967) and Minnesota Vikings (1968-1979).
brett farve
Peyton Manning
TIE: Bill Kay had 7 intercetions in 1979 Phil Mateja had 7 interceptions in 1952
Career interceptions thrown, is Terry Bradshaw with 210. The single season Steelers record is Jim Finks in 1955 with 26 interceptions thrown.
Paul Krause is the all-time leader in interceptions with 81, Emlen Tunnell is second with 79. In terms of throwing, Brett Favre has the most interceptions thrown.
brett farve
rod Wilson holds the nfl record for interceptions retuned for touchdowns with 12.
Peyton Manning with 28.
Antonio Langham
Bret favre
Rod Woodson with 12.
Peyton Manning
Night Train Layne
TIE: Bill Kay had 7 intercetions in 1979 Phil Mateja had 7 interceptions in 1952
Baltimore LB Don Shinnick holds the record all-time record for linebackers with 37 career interceptions. Shinnick played from 1957-1969. Amongst active players, Ray Lewis leads the league with 29 career interceptions. Source: Playerfilter
Former Ravens Safety Ed Reed (#20) holds the Ravens franchise record for the most interceptions at 61.He also holds NFL and Ravens records for yards returned following interceptions, as well as being the only NFL player in history to return an interception, punt, blocked punt, and fumble for a touchdown.
There are actually four different quarterbacks who hold that record. Brett Farve, Frank Filchock, Bobby Layne and Norm Van Brocklin all threw 6 interceptions in a single playoff game.