In MLB, that was 4 against the Philadelphia Athletics on June 3, 1932.
1931 Lou Gehrig and Babe Ruth tied for the American League lead in home runs in 1931 with 46.
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Lou Gehrig hit 23 career grand slam home runs, the most by any player in Major League Baseball history.
Lou Gehrig of the New York Yankees against the Philadelphia Athletics on June 3, 1932.
Reggie Jackson and Chase Utley hold the record for most home runs in a World Series with 5. Players with 4 home runs in a World Series are Lou Gehrig, Babe Ruth, Hank Bauer, Barry Bonds, Duke Snider and Gene Tenace.
Lou Gehrig
Lou Gehrig with 493.
Lou Gehrig hit 35 home runs, 2 of them grand slams, in the 1929 season.
Lou Gehrig's highest home run total was 49. He achieved that in 1934 and 1936.
1931 Lou Gehrig and Babe Ruth tied for the American League lead in home runs in 1931 with 46.
Lou Gehrig played in 13 games in 1923, and hit 1 home run.
Drive in runs.
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Lou Gehrig hit 23 career grand slam home runs, the most by any player in Major League Baseball history.
Lou Gehrig led the Major Leagues in home runs in 1936 with 49
Lou Gehrig of the New York Yankees against the Philadelphia Athletics on June 3, 1932.
Lou Gehrig hit 145 home runs during that time span. 1932 (34), 1933 (32), 1934 (49) & 1935 (30).