The NFL record for sacks in a game is 12 and has been done 5 times:
1) Dallas vs. Pittsburgh, Nov. 20, 1966
2) St. Louis vs. Baltimore, Oct. 26, 1980
3) Chicago vs. Detroit, Dec. 16, 1984
4) Dallas vs. Houston, Sept. 29, 1985
5) NY Giants vs. Philadelphia, Sept. 29, 2007
Derrick Thomas with 7
8 sacks against steelers and won
Current record is 200.0 sacks by Bruce Smith, Buffalo, 1985-1999; Washington, 2000-03 David ``Deacon`` Jones has the unofficial record, he kept all of his sacks written down in a book he kept and had a total of I think 226.5 sacks
Troy Edwards from La Tech vs. Nebraska 1998
On November 11, 1990, Kansas City Chiefs linebacker Derrick Thomas set the NFL record for the most sacks in one game. Thomas sacked Seattle Seahawks quarterback Dave Krieg seven times.
probably auburn vs alabama 2005 auburn had 11 sacks in that game war eagle.
Derrick Thomas with 7
osi unenora 6 SACKS AGAINST EAGLES IN 2007.
The 1988 Miami Dolphins hold that record. They managed to allow just 7 sacks in 16 games.
Kamerion Wimbley holds the record for the most sacks in one game by a Raider in one game of football. The game was played on November 10, 2011 against the San Diego Chargers. He had 4 sacks that game.
8 sacks against steelers and won
Montana
i believe it was Brett Favre
Shaquille O'Neal
Current record is 200.0 sacks by Bruce Smith, Buffalo, 1985-1999; Washington, 2000-03 David ``Deacon`` Jones has the unofficial record, he kept all of his sacks written down in a book he kept and had a total of I think 226.5 sacks
Jeff teague of wake forest (2009)
Georgia Tech holds the record for most points in one game with 222 on Cumberland.