No. Joe Castle is a fictional first baseman who played for the Cubs in the novel Calico Joe by John Grisham. His character is based on Ray Chapman, the only MLB player killed by a pitch.
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Joe Quest was born November 16, 1852, in New Castle, PA, USA.
Joe Kraemer debuted on August 22, 1989, playing for the Chicago Cubs at Wrigley Field; he played his final game on June 25, 1990, playing for the Chicago Cubs at Wrigley Field.
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Joe Wallis debuted on September 2, 1975, playing for the Chicago Cubs at Wrigley Field; he played his final game on September 30, 1979, playing for the Oakland Athletics at Oakland Coliseum.
Joe Strain debuted on June 28, 1979, playing for the San Francisco Giants at Candlestick Park; he played his final game on June 2, 1981, playing for the Chicago Cubs at Wrigley Field.