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Derrick Thomas of the Kansas City Chiefs had a record-setting 7.0 sacks on November 11, 1990 in a game against the Seattle Seahawks. Tied for 2nd on the list at 6.0 sacks are Fred Dean (49ers, '83), Osi Umenyiora (Giants, '07), and Derrick Thomas (Chiefs, '98).

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Q: Sack record in one game
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