On November 4, 2007, rookie running back Adrian Peterson of the Minnesota Vikings rushed 30 times for 296 yards and three touchdowns against the San Diego Chargers in Minneapolis. The effort broke the NFL single-game rushing record of 295, set by Baltimore Ravens running back Jamal Lewis in 2003.
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As of the 2008 season, that is Adrian Peterson of the Vikings who rushed for 296 yards in a game against the Chargers in 2007.
Minnesota Viking Adrian Peterson, 296 yards, November 4, 2007 vs. San Diego Chargers. He was a rookie at the time.
6 by Ernie Nevers of the Chicago Cardinals in a game against the Chicago Bears in 1929.
Adrian Peterson in 2007, he rushed for 296 yards vs the San Diego Chargers defense.
Timmy Smith of the Washington Redskins rushed for 204 yards in Super Bowl XXII when the 'Skins beat the Denver Broncos 42-10.
Most rushing yards, game: 314, Eddie George(November 11, 1995 vs. Illinois)
Marcus depree
Drew Bledsoe has the most negative rushing yards in NFL history.
Ted Gin Jr. had the most he returned to kick returns back for over 200 yards.
jamal Lewis had 295 yards 4 the Baltimore ravens