Most rushing yards, game: 314, Eddie George(November 11, 1995 vs. Illinois)
Marcus depree
Drew Bledsoe has the most negative rushing yards in NFL history.
jamal Lewis had 295 yards 4 the Baltimore ravens
As of the start of the 2007 season, Walter Payton has the second most career rushing yards in NFL history with 16,726. Emmitt Smith is first with 18,355 and Barry Sanders is third with 15,269.
Most rushing yards, game: 314, Eddie George(November 11, 1995 vs. Illinois)
O.J. Simpson with 2003 rushing yards for the 1973 Buffalo Bills.
Cory dillon
chris Johnson
All-time rushing yards (16,726; now surpassed), Most 100-yard rushing games (77), and Most yards gained rushing in a game (275; now surpassed).
Adrian Peterson - 296 Rushing yards on November 4th 2007 against the San Diego Chargers
Drew Bledsoe has the most negative rushing yards in NFL history.
Marcus depree
From most news Willie Parker of the Pittsburgh Steelers.
Drew Bledsoe has the most negative rushing yards in NFL history.
Rashard Mendenhall had the most rushing yards with 63 yards in Super Bowl XLV.
296 Adrian Petterson