The MLB record for runs scored in a game is 36 by the Chicago Colts against the Louisville Colonels in 1897. The Colts won the game 36-7.
The record for the modern era (1900-present) is 30 by the Texas rangers against the Baltimore Orioles in 2006. Rangers won 30-3.
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Reggie. Jackson
Barry Bonds has the most home runs in Major League Baseball (762).
In Major League Baseball, Barry Bonds has hit the most home runs.
121
Hank Aaron 755