Through the 2012 season, Peyton Manning has thrown 436touchdowns in his career.
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In the NFL, 125 ... 115 for the Saints, 8 for the Oilers, and 2 for the Vikings.
Brett Favre has more career touchdown passes and more career interceptions thrown than Peyton Manning
Peyton Manning
Tom Brady, Peyton Manning, Dan Marino, Kurt Warner
Dan Marino of the Miami Dolphins in the 1998 season.Dan Marino.Brett Favre was the second, and so far they are the only two. Unless he gets injured, Peyton Manning has a good chance to join them in 2010 or 2011 (he needs 34 more TD passes).
The NFL Record for most touchdown passes in a game is 7. This has been done by: Sid Luckman - 1943 Adrian Burk - 1954 George Blanda - 1961 Y.A. Tittle - 1962 Joe Kapp - 1969 Peyton Manning - 2013