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In MLB, no, although there was one game in MLB history where both pitchers had a no-hitter through 9 innings. That was on May 2, 1917 in a game between the Cincinnati Reds and Chicago Cubs when Hippo Vaughn of the Cubs and Fred Toney of the Reds had no-hitters going after 9 innings. Vaughn gave up two hits and a run in the 10th inning to lose his no-hitter but Toney retired the side without giving up a hit to preserve his no-hitter.

The fewest hits given up in an MLB game is 1. That was on September 9, 1965 in the game between the Chicago Cubs and Los Angeles Dodgers. Sandy Koufax of the Dodgers pitched a perfect game and Bob Hendley of the Cubs gave up 1 hit.

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On May 2,1917, Cubs Hippo Vaughn and Reds Fred Toney both had no-hitters after nine innings. Vaughn lost his in the 10th, but Toney completed the 10-inning no-hitter for the win.

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Q: Has there ever been 2 no hitters pitched in a game?
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