Frank Gore with 110 rushing yards.
Emmitt Smith,with 18,355 rushing yards, currently holds the record for the highest rushing yards in the game.
Terrell Davis of the Denver Broncos had the most rushing yards in 1998. He had 2008 yards and was the fourth running back in NFL history to rush for over 2000 yards.
That was Eric Dickerson of the Indianapolis Colts with 1,659 rushing yards.
Joseph Addai of the Colts who had 77 rushing yards
Beattie Feathers of the 1934 Chicago Bears with 1004 rushing yards.
Ahmad Bradshaw (New York Giants) with 72 rushing yards.
Terrell Davis - 2,008 yards.
Ahmad Bradshaw had 72 yards.
For a career that is Michael Vick with 7.1 yards per rushing attempt (through 10 games of the 2010 season). Most of the career leaders in this category are quarterbacks. The running back with the highest yards per rushing attempt is Marion Motley at 5.7. For a single season, the record is held by Vick of the 2006 Falcons and running back Beattie Feathers of the 1934 Bears with 8.4 yards per rushing attempt.
Terrell Davis of the Denver Broncos led the NFL in rushing yardage in 1998 with 2,008 yards.