Sergio Robles debuted on August 27, 1972, playing for the Baltimore Orioles at Memorial Stadium; he played his final game on September 13, 1976, playing for the Los Angeles Dodgers at Dodger Stadium.
Sergio Escalona debuted on May 17, 2009 and played his final game on September 7, 2011.
Sergio Ferrer debuted on April 5, 1974 and played his final game on September 28, 1979.
NFL player Sergio Brown played for Notre Dame.
NFL player Sergio Castillo played for West Texas A&M.
Mauricio Robles debuted on September 3, 2013, playing for the Philadelphia Phillies at Citizens Bank Park; he played his final game on September 26, 2013, playing for the Philadelphia Phillies at Citizens Bank Park.
Oscar Robles debuted on May 10, 2005, playing for the Los Angeles Dodgers at Dodger Stadium; he played his final game on October 1, 2007, playing for the San Diego Padres at Petco Park.
Rafael Robles debuted on April 8, 1969, playing for the San Diego Padres at Jack Murphy Stadium; he played his final game on June 10, 1972, playing for the San Diego Padres at Jack Murphy Stadium.
Sergio Ferrer debuted on April 5, 1974, playing for the Minnesota Twins at Metropolitan Stadium; he played his final game on September 28, 1979, playing for the New York Mets at Shea Stadium.
Sergio Valdez debuted on September 10, 1986, playing for the Montreal Expos at Stade Olympique; he played his final game on September 26, 1995, playing for the San Francisco Giants at Candlestick Park.
Sergio Escalona debuted on May 17, 2009, playing for the Philadelphia Phillies at Citizens Bank Park; he played his final game on September 7, 2011, playing for the Houston Astros at Minute Maid Park.
Sergio Mitre debuted on July 22, 2003, playing for the Chicago Cubs at Wrigley Field; he played his final game on July 15, 2011, playing for the New York Yankees at Yankee Stadium III.
Sergio Santos debuted on April 8, 2010, playing for the Chicago White Sox at U.S. Cellular Field; he played his final game on September 29, 2013, playing for the Toronto Blue Jays at Rogers Centre.