Rafael Robles debuted on April 8, 1969, playing for the San Diego Padres at Jack Murphy Stadium; he played his final game on June 10, 1972, playing for the San Diego Padres at Jack Murphy Stadium.
Rafael Almeida debuted on July 4, 1911 and played his final game on July 18, 1913.
Rafael Batista debuted on June 17, 1973 and played his final game on April 27, 1975.
Rafael Belliard debuted on September 6, 1982 and played his final game on April 9, 1998.
Rafael Betancourt debuted on July 13, 2003 and played his final game on August 22, 2013.
Rafael Bournigal debuted on September 1, 1992 and played his final game on October 3, 1999.
Rafael Carmona debuted on May 18, 1995 and played his final game on June 12, 1999.
Rafael Dolis debuted on September 26, 2011 and played his final game on May 26, 2013.
Rafael Santo Domingo debuted on September 7, 1979, playing for the at ; he played his final game on September 30, 1979, playing for the at .
NFL player Rafael Bush played for South Carolina State.
Sergio Robles debuted on August 27, 1972, playing for the Baltimore Orioles at Memorial Stadium; he played his final game on September 13, 1976, playing for the Los Angeles Dodgers at Dodger Stadium.
Rafael Batista debuted on June 17, 1973, playing for the Houston Astros at Astrodome; he played his final game on April 27, 1975, playing for the at .
Mauricio Robles debuted on September 3, 2013, playing for the Philadelphia Phillies at Citizens Bank Park; he played his final game on September 26, 2013, playing for the Philadelphia Phillies at Citizens Bank Park.