Bucknell
Ohio State's first interscholastic football game was played in May, 1889 against Ohio Wesleyan. Ohio State won 20-14.
There wasn't a first state, cause then they would have no-one to play against, a few teams came out at the same time to start a football league.
Miami, Florida
The first American collegiate game of football was played in 1869 in New Brunswick, New Jersey by Rutgers College and Princeton University. Rutgers won this game. From that point on American football has become a billion dollar collegiate and professional sport. This not to be confused by the world's game of football which is called soccer in America.
Ohio State's first interscholastic football game was played in May, 1889 against Ohio Wesleyan. Ohio State won 20-14.
Desmond Howard
October first 2011 against msu
1893. Their first game was against Lewis and Clark in Corvallis and Oregon State won 62-0.
First non-collegiate team was the Canton Bulldogs, formed in 1905. But college football had been being played for nearly 40 years by this time.
Cannon firings at Rutgers football games date back to 1931. It's not necessarily the earliest but it gets the ball rolling.
The first intercollegiate football game was played on November 6, 1869 between Rutgers and Princeton with Rutgers winning 6-4.